[摘要] 目的 分析临床分离的376株鲍曼不动杆菌的临床分布及耐药性，为临床感染的诊断与治疗提供依据。方法 2013年9月～2015年7月在沈阳医学院附属中心医院患者送检的各类标本中通过分离培养获得鲍曼不动杆菌376株，采用纸片琼脂扩散法对上述菌株进行药物敏感试验，对其临床分布及药敏结果进行回顾性分析。结果 376株鲍曼不动杆菌大多分离自痰液(83.2%)，主要来自于ICU病房(54.0%)；药敏分析结果显示，上述菌株对亚胺培南和美洛培南的敏感率分别达73.4%、64.4%，而对氨曲南的耐药率达83.5%。 结论 鲍曼不动杆菌是医院感染中重要的病原菌，其对抗菌药物的耐药率高，且常表现为多重耐药，临床要重视合理使用抗菌药物，减少多重耐药菌株的产生。

    [关键词] 鲍曼不动杆菌；临床分布；耐药性

    [中图分类号] R446.5 [文献标识码] A [文章编号] 1674-4721(2016)02(c)-0112-03

    [Abstract] Objective To analyze clinical distribution and drug resistance of 376 strains of Acinetobacter baumannii isolated form clinic to provide evidence for diagnosis and treatment of clinical infection. Methods 376 strains of Acinetobacter baumannii isolated from various specimens delivered from Central Hospital Affiliated to Shenyang Medical College from September 2013 to July 2015.These strains were performed drug sensitivity test using agar-diffusion method.The clinical distribution and drug sensitivity results were analyzed retrospectively. Results The majority of these resistant strains were isolated from sputum (83.2%) ......